Name: Xgeva 120mg Injection
SKU: 10022
Availability: InStock

Introduction Of Xgeva 120mg Injection

Xgeva 120mg Injection consists of the active ingredient Denosumab. It is a medication used to treat osteoporosis, characterized by weakened bones. It is also prescribed to prevent bone complications in patients with certain types of cancer, such as multiple myeloma and bone metastases. Xgeva 120mg Injection works by inhibiting a protein called RANK ligand, which plays a role in the breakdown of bone tissue. Studies proved it can significantly increase bone density, reducing fracture risk in postmenopausal women with osteoporosis and patients with cancer-related bone loss. Close monitoring of renal function may be necessary for patients with moderate renal impairment.

Xgeva 120mg Injection should not be used in individuals with known hypersensitivity or allergic reactions to its components. Adequate calcium and vitamin D supplementation is required to ensure during the treatment. It is not approved for use in children and adolescents. Its safety and effectiveness in pediatric populations have not been established, so its use is contraindicated in individuals under 18. This medication should be used cautiously in individuals with pre-existing hypoparathyroidism, characterized by low parathyroid hormone levels.

Therapeutic Effects of Xgeva 120mg Injection

Xgeva 120mg Injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Interaction of Xgeva 120mg Injection with other drugs

Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Xgeva 120mg Injection and reduce effectiveness by causing undesirable side effects.

More Information about Xgeva 120mg Injection

Xgeva 120mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
Do not freeze it.
Keep in the original package.
Keep away from light, moisture, and heat.
Keep away from children and pets.
Avoid taking double doses for missed doses.

How to consume Xgeva 120mg Injection

Xgeva 120mg Injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual’s condition and response to the medication and should be determined by a healthcare provider.

Safety Advices for Xgeva 120mg Injection

Pregnancy

Consult your doctor

The safety of using Xgeva Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women .

Breast Feeding

Consult your doctor

Whether Xgeva Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.

Lungs

Consult your doctor

If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Xgeva Injection.

Liver

Consult your doctor

Xgeva Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment.

Alcohol

Unsafe

It is generally recommended to avoid or limit alcohol consumption while taking Xgeva Injection. Alcohol can interact with this medication, potentially increasing the risk of side effects.

Driving

Consult your doctor

Patients receiving Xgeva Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient’s ability to drive or operate machinery safely.

Side Effects of Xgeva 120mg Injection

Serious:

Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
Atypical femoral fractures
Hypocalcemia (low blood calcium levels)

Common:

Injection site reactions
Back pain
Musculoskeletal pain
Infections
Abdominal pain
Headache
Hypophosphatemia (low blood phosphate levels)

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