Thymogam 250mg Injection

Thymogam 250mg Injection contains the active ingredient Antithymocyte Immunoglobulins. It is a purified and sterile form of gamma globulin. It is isolated from the hyperimmune plasma of horses immunized with human white blood cell components. It is used after kidney transplantation and other therapies to treat and delay organ rejection.

After solid organ transplantation, the body generates an aggressive immune response because it recognizes the transplanted organ’s antigens as a foreign antigen. Thus, treatment with immunosuppressive agents is necessary after an organ transplant to prevent organ rejection.

Aplastic anemia is a condition characterized by the failure of the bone marrow to produce sufficient blood cells. Thymogram 250mg Injections are used to treat severe aplastic anemia, suppress the immune system, and reduce the immune-mediated destruction of bone marrow cells. This helps to restore normal blood cell production. Thymogam 250mg Injection can decrease the need for high doses and prolonged use of corticosteroids in immunosuppressive treatments, minimizing side effects and risks.

Individuals with known hypersensitivity or previous severe allergic reactions to Thymogam 250mg Injection or any of their components should not receive it. Live vaccines should generally be avoided during treatment. Individuals with active infections, particularly severe or systemic infections, should only receive until the infection is adequately treated and resolved.

The therapeutic effect of Thymogam 250mg Injection is the suppression of the immune response by targeting and depleting T lymphocytes. This effect is beneficial in preventing organ rejection in solid organ transplantation, where this medication helps increase the success of transplantation and improve graft survival rates.  Additionally, these are used in treating conditions such as aplastic anemia and graft-versus-host disease (GVHD), where the immune system attacks the body’s cells or tissues. Modulating the immune response reduces immune-mediated damage, alleviates symptoms, and promotes the restoration of normal cell production.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Thymogam 250mg Injection and reduce their effectiveness by causing undesirable side effects.

• Store in refrigerated conditions between 2°C and 8°C (36°F to 46°F).
• Protect the medicine from light and excessive moisture.
• Keep the medicine out of reach of children and pets
• Take only a partial dose to compensate for a forgotten dose.

Thymogam 250mg Injection is typically administered intravenously injection in a hospital or clinical setting. Your healthcare provider will determine the specific dosage and infusion rate based on factors such as the condition being treated, your body weight, and your response to the medication.

Serious

• Allergic reactions
• Infections
• Blood disorders (anemia, thrombocytopenia)
• Kidney dysfunction
• Neurological complications

Common

• Urinary tract infection
• Stomach pain
• High BP
• Nausea
• Fever, headache, and chills
• Anxiety
• Skin reactions