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Pegstim 6mg Injection
Pegfilgrastim
Uses of Pegstim 6mg Injection
Pegstim 6mg is a prescription Injection, and it is used to treat
- Decrease the chance of infection caused by low levels of white blood cells in patients with certain types of cancer (non-myeloid) receiving bonemarrow suppressing anti-cancer drugs.
- To increase the survival rate in patients receiving radiation therapy that suppresses bone marrow activity.
Product Description
Introduction to Pegstim 6mg Injection
Pegstim 6mg Injection contains the active ingredient Pegfilgrastim. It belongs to the class granulocyte colony stimulated factor approved by FDA to decrease the risk of developing febrile neutropenia ( occurrence of fever or infection with low WBC count) and the duration of neutropenia (Low white blood cell count) when receiving bonemarrow suppressive chemotherapy drugs. It is also indicated to increase survival rate in patients exposed to radiation therapy which can cause severe and life-threatening damage to bone marrow. It acts on blood-forming cells, thereby stimulating cell multiplication and cell function activation.
Pegfilgrastim is a protein synthesized through biotechnology in E. coli bacteria. It belongs to the cytokine family of proteins and is very similar to a natural protein (granulocyte-colony stimulating factor) produced by your body. White blood cells (WBC) are important because they help your body fight infection. These cells are highly sensitive to the effects of chemotherapy, which might cause a decrease in the number. If your WBC decreases, your body may not have enough cells to combat bacteria, putting you at risk of infection.
Inform your physician if you have or ever had liver disease, fever or infection, kidney problems, heart problems, or a family history of kidney diseases before starting the treatment with this Injection. Do not take this Injection if you are allergic to pegfilgrastim. Filgrastim or any of the other ingredients in this Injection. Report any symptoms of left upper abdominal pain, shoulder pain, and respiratory problems immediately to your doctor. The most common side effects of Pegstim 6mg injection are pain in the bones, arms, and legs.
Therapeutic Effects of Pegstim 6mg Injection
Pegstim 6mg Injection is a colony-stimulating factor that exerts its action by acting on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation.
Interaction of Pegstim 6mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Pegstim 6mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Pegstim 6mg Injection
- Store Pegstim 6mg Injection in a refrigerator (2°C – 8°C). Do not freeze.
- Do not shake this Injection
- Discard the Injection if it has been stored at room temperature for more than 48 hours.
- Keep it out of reach from children and pets.
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor immediately for advice.
How to consume Pegstim 6mg Injection
The Injection will be administered in the fatty tissues just under your skin (subcutaneously) by a qualified healthcare professional in a hospital setting. The dose and frequency of administration will be decided by your doctor based on your disease condition and other factors.
If your physician decides that Pegstim 6mg Injection can be administered at home by you or your caregiver, then read the “Instructions for use” carefully from the package insert that comes with the Injection. Your doctor or other healthcare professionals will train you on self-administration. Do not administer the Injection if you have not been trained and not sure about the administration procedure.
Safety Advices for Pegstim 6mg Injection
Pregnancy
Pegstim 6mg Injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is unsafe to breastfeed during the treatment with this Pegstim 6mg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Lungs
It is unknown whether Pegstim 6mg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unknown whether Pegstim 6mg Injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.
Alcohol
It is unsafe to consume alcohol with Pegstim 6mg Injection. Please consult your doctor for more advice.
Driving
It is unsafe to travel, drive vehicles or operate heavy machinery after taking (1 hour) Pegstim 6mg Injection. Please consult your doctor.
Side Effects of Pegstim 6mg Injection
Side effects are unwanted symptoms caused by Injections. Even though all drugs cause side effects, not everyone gets them.
Common
- Pain in the bones, joints and muscles
- Pain at the site of Injection
- Itchiness and skin rash
- Nausea
- Headaches
- Dizziness and tiredness
Serious
- Inflammation of Aorta
- Capillary leak syndrome (plasma leaks out of tiny blood vessels)
- Hypersensitivity reactions
- Changes in urine color
- Swelling in hands, feet, face, and abdomen
- Difficulty in breathing
- Sickle cell anemia
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