Meqsel 2mg Tablet

Trametinib

Uses of Meqsel 2mg Tablet

  • Metastatic melanoma
  • Use in combination with dabrafenib for improved treatment outcomes of melanoma
  • Used in treatment of non-small cell lung carcinoma
  • Used in treating metastatic anaplastic thyroid cancer
  • Metastatic solid tumours

Introduction to Meqsel 2mg Tablet

Meqsel 2mg Tablet has Trametinib as an active agent. It is a prescription medication used to treat certain types of cancers. Cancer is a disorder in which cells multiply uncontrolled and abnormally. This medication inhibits the cell growth and division of cancer cells and used in treatment of advanced melanoma. It is typically used with another drug (dabrafenib) to improve treatment outcomes. This medication is used to treat skin cancer called melanoma which cannot be removed by surgery or has spread to other parts of the body. It also prevents melanoma from returning after being removed from surgery. Also used to treat a kind of lung cancer called non-small cell lung cancer (NSCLC).

Like all medications, it can cause side effects. The most common side effects include rash, diarrhea, nausea, vomiting, fatigue, and peripheral edema (hand and foot swelling). Talk to your physician if you have liver disorders, kidney disorders, breathing problems, heart diseases, or eye problems before taking Meqsel 2mg Tablet. It is not recommended for adolescents and children under the age of 18 and for also who are allergic to it or one of its components. The recommended dose is one tablet daily, taken orally with or without food.

Therapeutic Effects of Meqsel 2mg Tablet

Meqsel 2mg Tablet works by blocking the activity of a protein called Mitogen-activated protein kinase kinase (MEK), which is part of the Mitogen-activated protein kinase (MAPK) signaling pathway. This pathway is critical in regulating cell growth, division, and survival. It  helps slow or stop cancer cell growth and spread by blocking MEK.


Interaction of Meqsel 2mg Tablet with other drugs

You should tell the doctor about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Meqsel 2mg Tablet  and reduce effectiveness by causing undesirable side effects.


More Information about Meqsel 2mg Tablet

  • Meqsel 0.5 mg Tablet  should be stored at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep in original packaging.
  • Protected from light and moisture.
  • Keep out of the reach of children and pets.

How to consume Meqsel 2mg Tablet

Meqsel 2mg Tablet  is usually taken orally as a tablet. It can be taken either with or can also be taken without food. Your specific condition, such as medical conditions, age, weight, and overall health, will decide the dosage and duration of treatment. It is essential to follow the instructions provided by the healthcare provider or pharmacist when taking. Generally, the tablet should be swallowed whole with a full glass of water. You should not crush, chew, or break the tablet. If a dose is missed, it is important to take it as soon as possible unless it is almost time for the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. It would help if you did not take two drug doses together to compensate for a missed dose.


Safety Advices for Meqsel 2mg Tablet

 

Pregnancy

Meqsel 2mg Tablet is unsafe for pregnant women as it may cause foetal harm. It is not recommended to take it during pregnancy.

 

Breast Feeding

Meqsel 2mg Tablet is unsafe during breastfeeding. Because of the potential risk to the infant, breastfeeding is not recommended during treatment.

 

Lungs

Meqsel 2mg Tablet has been associated with some lung-related side effects, although these are relatively uncommon. Consult your doctor if you have any lung diseases before starting the treatment.

 

Liver

Regular monitoring of liver function tests is recommended because Meqsel 2mg Tablet has been associated with liver injury in some patients. It is important to monitor liver function regularly in patients, particularly in those with pre-existing liver disease or a history of liver problems.

 

Alcohol

It is generally recommended that patients taking Meqsel 2mg Tablet avoid or limit their alcohol intake, as alcohol can increase the risk of liver damage and exacerbate any liver-related side effects.

 

Driving

Meqsel 2mg Tablet may cause side effects such as fatigue, dizziness, or blurred vision that can impair a patient’s ability to drive or operate machinery safely. If a patient experiences any side effects that affect their ability to drive or operate machinery safely while taking it, they should avoid these activities and seek medical advice.


Side Effects of Meqsel 2mg Tablet

Side effects are unwanted symptoms that occur due to medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

  • Heart failure
  • Irregular heartbeat
  • Shortness of breath
  • Liver injury or hepatitis
  • Retinal detachment
  • Gastrointestinal perforation (a hole or tear in the stomach or intestine)
  • Stevens-Johnson syndrome (a severe skin reaction)

Common:

  • Nausea
  • Diarrhoea
  • Fatigue
  • Skin rash
  • Acne
  • Dry skin
  • Headache
  • Fever
  • Swelling in the hands or feet
  • High blood pressure
  • Eye problems, such as blurred vision or sensitivity to light

Brand

Novartis

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