Zobisted 2mg Injection

Introduction to Zobisted 2mg Injection

Zobisted 2mg injection is a chemotherapeutic medication that belongs to the class of drugs called Proteasome inhibitors. It contains the active compound bortezomib. It is used to treat multiple myeloma and mantle cell lymphoma. This medication is concomitantly used with other chemotherapy medicines like pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone or thalidomide for patients who have not started treatment and are unsuccessful or ineligible for blood stem cell transplant treatment.

It is not recommended to take Zobisted 2mg injection if you are allergic to active compounds or any other ingredients of this medicine. It is not advised to take this medicine if you have a compromised immune system. If you have an active infection, let your doctor know before beginning any treatment. It is not recommended to use Zobisted 2mg injection in children and adolescents. It is not recommended to use this medication in patients with hepatitis. Inform your doctor if you have gastrointestinal disorders, hepatic disorders, thrombocytopenia (low platelet count), neutropenia (low white blood cell count), tumor lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), neuropathy (nerve malfunction), cardiac disorders, severe lung problems, pulmonary disorders and posterior reversible encephalopathy syndrome disorders before beginning the treatment with this medication. You are advised to monitor blood counts and hepatic enzymes throughout the treatment period.

The use of Zobisted 2mg injection during pregnancy and breastfeeding is not recommended and will be determined by the doctor only if absolutely necessary as it may cause harm to the developing foetus. It is recommended to use effective contraceptive methods during the therapy and 3 months after completion. Inform your doctor if you are pregnant or planning to get pregnant to know about effective contraceptive methods. It is necessary to inform your physician about all the medicines, over the counter drugs, vitamin and herbal supplements you are taking before the start of therapy.

Therapeutic Effects of Zobisted 2mg Injection

Zobisted 2mg injection works by exerting a toxic effect on cancer cells. It inhibits the 26S proteasome and blocks a major cell signaling pathway. This inhibition of the signaling pathway makes the cancer cells sensitive to chemotherapy. By inhibiting the proteasome, Zobisted 2mg injection disrupts the normal process of protein degradation within the cell. This leads to the accumulation of misfolded or damaged proteins, which are toxic to the cell.

The accumulation of misfolded proteins triggers a series of cellular responses, including the activation of stress pathways and the induction of apoptosis. This medicine also enhances the build-up of a protein and minimizes cancer cell growth and multiplication.

Interaction of Zobisted 2mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Zobisted 2mg injection and reduce effectiveness by causing undesirable side effects.

More Information about Zobisted 2mg Injection

Store in a refrigerator (2°C – 8°C).
Do not freeze.
Protect the medicine from light and excessive moisture.
Keep the medicine out of reach of children and pets
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

How to consume Zobisted 2mg Injection

Zobisted 2mg injection is administered by injection intravenously in your vein or subcutaneously under the skin. It is given in by a healthcare professional in a hospital setting.

The dosage and frequency of Zobisted 2mg injection will depend on various factors, including the patient’s age, weight, overall health, and the type and stage of disease being treated. It’s important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. Do not self-administer this injection.

If a dose is missed, it should be taken as soon as possible unless it’s within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It’s important not to take a double dose of Zobisted 2mg injection to make up for a missed dose.

Safety Advices for Zobisted 2mg Injection

Pregnancy

Zobisted 2mg injection should not be taken while pregnant unless prescribed by a physician. Your physician will prescribe it only if necessary on an individual case to case basis. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 3 months after the last dose.

Breast Feeding

It is not recommended to use Zobisted 2mg injection during breastfeeding. Your physician will prescribe it only if necessary. You should consult your physician regarding the safe period to restart breastfeeding after this treatment.

Lungs

Zobisted 2mg injection should be used with caution in individuals who have respiratory issues. Let your doctor know if you have any lung conditions before starting any treatment.

Liver

Zobisted 2mg injection should be taken cautiously in patients with liver problems. If you have liver disease or an infection with hepatitis, let your doctor know before beginning this treatment. Your doctor will periodically check on the health of your liver.

Alcohol

Zobisted 2mg injection is metabolized in the liver, and excessive alcohol consumption can also lead to liver damage. The use of two concomitantly may potentially increase the risk of liver problems.

Driving

Zobisted 2mg injection may impair your ability to operate machinery, ride a bike, or drive. After taking this medication, tiredness, dizziness and blurred vision are expected. If a patient experiences any side effects that affect their ability to drive or operate machinery safely while taking Zobisted 2mg injection, they should avoid these activities and seek medical advice

Side Effects of Zobisted 2mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

Peripheral neuropathy
Hypotension
Cardiac toxicity
Posterior Reversible Encephalopathy Syndrome (PRES)
Tumor Lysis Syndrome
Hepatic Toxicity
Thrombotic Microangiopathy

Common:

Loss of appetite
Sensitivity, tingling and burning sensation of the skin
Nausea, vomiting, and diarrhea
Mouth ulcers
Constipation
Muscle and bone pain
Hair loss
Fever
Reduction in blood cell count
Reduced kidney function
Shivering
Infections
Dehydration
Stomach problems
Difficulty sleeping, anxiety, mood swings, depressed mood

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