Introduction Of Rituxirel 100mg Injection
Rituxirel 100mg Injection contains the active constituent rituximab. It is used for several different disease conditions in adults. It is used alone or with other medications to treat non-hodgkin’s lymphoma and chronic lymphocytic leukemia . It is also indicated to treat moderate-to-severe rheumatoid arthritis in combination with methotrexate in adults. Other uses include granulomatosis with polyangiitis or microscopic polyangiitis in adults and children 2 years of age and older. It is also used to treat moderate to severe pemphigus vulgaris (an autoimmune condition that causes painful blisters on the skin and lining of the mouth, throat, nose, and genitals.
Rituxirel 100mg injection belongs to the class of medications called anti-CD20 monoclonal antibodies. Do not take this injection if you are allergic to rituximab or any other ingredients of this medicine, have a weak immune system, or have any severe active infection.
Common side effects of Rituxirel 100mg injection include infection of the blood, reduced red blood cells, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and low or high blood pressure. Use effective contraceptives during the treatment and 12 months after the last dose if you can get pregnant.
Therapeutic Effects of Rituxirel 100mg Injection
Rituxirel is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes . When this medicine binds to the B-cell, it induces cell death in NHL and CLL. The binding action blocks cell activation and growth and cause anticancer effects. It inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.
Interaction of Rituxirel 100mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. In particular, tell your doctor if you are taking medicines for blood pressure or other heart conditions. Certain medications may interact with Rituxirel 100mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Rituxirel 100mg Injection
- Store Rituxirel 100mg injection in the refrigerator (2°C to 8°C)
- Do not freeze
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Rituxirel 100mg Injection
It should only be administered by a trained doctor or nurse. Do not self-administer the injection. Before giving Rituxirel injection, you will be given other medications (pre-medication) to reduce the possible side effects. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for any unwanted side effects.
Safety Advices for Rituxirel 100mg Injection
Pregnancy
Consult your doctor
Rituxirel injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Breast Feeding
Consult your doctor
Breastfeeding is not recommended in patients taking Rituxirel injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
Consult your doctor
It is unknown whether Rituxirel injection can be used in patients with lung disorders.
Liver
Consult your doctor
Whether Rituxirel injection can be used in patients with liver impairment is unknown.
Alcohol
Unsafe
Consuming alcohol may affect the effectiveness of Rituxirel injection. Stop consuming alcohol if you are taking this medicine.
Driving
Consult your doctor
Caution is required while driving and operating machinery when you take Rituxirel injection because it may cause dizziness, sleepiness, tiredness, and risk of falling.
Side Effects of Rituxirel 100mg Injection
Common
- Swelling in the face and body
- Diarrhea and nausea
- Itchy skin
- Anemia
Serious
- Increased or decreased blood pressure
- Chest pain
- Hypersensitivity reactions




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