Introduction of Rasby 1.5 mg Injection
Rasby 1.5 mg Injection is a prescription medicine used to treat certain types of cancers. It contains Rasburicase, an enzyme that helps manage high uric acid levels in the blood, often seen in patients undergoing chemotherapy for cancers like leukemia, lymphoma, or other malignancies. By lowering uric acid levels, it helps prevent complications such as tumor lysis syndrome (TLS), which can occur when cancer cells break down rapidly.
Description of Rasby 1.5 mg Injection
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Composition: Each injection contains 1.5 mg of Rasburicase.
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Formulation: Injectable solution for intravenous use.
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Therapeutic Class: Enzyme therapy / anticancer supportive care.
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Mechanism of Action: Rasburicase converts uric acid into a more soluble compound (allantoin), which is easily eliminated by the kidneys. This reduces uric acid levels quickly and protects the kidneys from damage due to TLS.
Benefits
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Rapidly lowers high uric acid levels caused by tumor breakdown during chemotherapy.
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Prevents complications such as acute kidney injury and other metabolic issues related to tumor lysis syndrome.
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Supports safer chemotherapy by reducing the risk of severe side effects from uric acid accumulation.
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Improves overall safety and treatment outcomes in high-risk cancer patients.
How to Use
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Administered intravenously by a healthcare professional in a hospital or clinic setting.
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Dosage and frequency are determined by the patient’s weight, uric acid levels, and type of cancer treatment.
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The injection should be prepared and given according to strict medical protocols to ensure safety.
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Continuous monitoring of uric acid levels, kidney function, and other blood parameters is recommended during treatment.
Uses
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Prevention and management of tumor lysis syndrome (TLS) in patients undergoing chemotherapy for:
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Leukemia
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Lymphoma
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Other rapidly growing cancers
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Reduces risk of kidney damage and other metabolic complications associated with TLS.
Side Effects
Common side effects:
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Fever
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Headache
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Nausea or vomiting
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Diarrhea
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Fatigue
Serious but rare side effects:
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Allergic reactions (rash, swelling, itching, breathing difficulty)
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Hemolysis (breakdown of red blood cells), especially in patients with G6PD deficiency
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Low blood counts (anemia, low platelets, low white blood cells)
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Kidney function changes
⚠️ Safety Advice
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Only for use under hospital supervision.
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Patients should be screened for G6PD deficiency before administration to prevent hemolysis.
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Regular monitoring of uric acid, kidney function, and blood counts is essential.
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Inform your doctor of all medications and pre-existing conditions before receiving Rasby Injection.
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Not recommended for patients with known hypersensitivity to Rasburicase or similar proteins.




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