Nexben 100mg Injection

Introduction to Nexben 100mg Injection

Nexben 100mg Injection is an antineoplastic drug belonging to the class of alkylating agents, containing the active ingredient Bendamustine. It is used to prevent and treat chronic lymphocytic leukaemia (cancer of blood and bone marrow), non-Hodgkin’s lymphomas (cancer that forms in the lymph system, part of the immune system), and multiple myelomas (cancer of plasma cells, type of white blood cell).

The common side effects that are likely to occur with this medicine are headache, insomnia, fatigue, loss of appetite and rashes. Some serious side effects also include bone marrow suppression, tumor lysis syndrome, and Hepatotoxicity. Inform your healthcare provider if these side effects concern you or persist for longer than usual. It is often combined with rituximab, an immunotherapy drug, to treat various subtypes of non-Hodgkin’s lymphoma, including follicular lymphoma, and mantle cell lymphoma. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. Consult your doctor immediately for more advice.

Treatment should not be started if your white blood cells (leukocytes) have fallen to counts below determined levels. Your doctor will determine these values at regular intervals. This medicine should not be used if you are allergic to this drug. If you are a man wanting to father a child, you should discuss the treatment with your physician, as taking this injection may reduce sperm production in men. This drug is typically given as an intravenous infusion over a period of 30-60 minutes. It is usually administered once every three to four weeks. Tell your physician about all the medications you have been taking recently, including herbal medicines and supplements, before taking Nexben 100mg Injection.

Therapeutic Effects of Nexben 100mg Injection

It is a type of alkylating agent, which works by causing DNA damage and disrupting the cell cycle, leading to cancer cell death. It forms covalent bonds with DNA, inhibits DNA repair enzymes, and blocks cell cycle progression. It is used as a cytotoxic drug that kills cancer cells by inhibiting their DNA and cell cycle.

Interaction of Nexben 100mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Nexben 100mg Injection and reduce effectiveness by causing undesirable side effects.

More Information about Nexben 100mg Injection

Store Nexben 100mg Injection in the refrigerator (2°-8°C). Do not freeze.
Keep it out of reach from children and pets.
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

How to consume Nexben 100mg Injection

The medicine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. This injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. During the infusion, you will be monitored for any side effects or reactions to the medication. The infusion usually takes several hours to complete, and you may need to receive multiple infusions over the course of several weeks.

Safety Advices for Nexben 100mg Injection

Pregnancy

Nexben 100mg Injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Breast Feeding

It is not known if Nexben 100mg Injection passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.

Lungs

It is not known whether Nexben 100mg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

Inform your doctor if you have any liver problems before taking Nexben 100mg Injection. Regular monitoring of liver function tests is recommended.

Alcohol

Consuming alcohol may affect the effectiveness of Nexben 100mg Injection. Stop consuming alcohol if you are taking this medicine.

Driving

It is unsafe to drive vehicles or operate heavy machinery after taking Nexben 100mg Injection, it may cause dizziness and impair your concentration.

Side Effects of Nexben 100mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

Severe allergic reactions
Bone marrow suppression
Abnormal liver function
Tumor lysis syndrome

Common

Infection, fever
Low blood cell count
Headache, dizziness
Nausea, vomiting
Increased blood level of creatinine and urea (chemical waste products)
Mucosal inflammation, sore mouth
Insomnia, fatigue
Hair loss, itching, rash
Diarrhea, constipation
Missed periods
Dehydration, loss of appetite
Low or high blood pressure

Recently Viewed