Koselugo 25mg Capsule
Selumetinib
Uses of Koselugo 25mg Capsule
- Melanoma treatment
- Neurofibromatosis type 1 (NF1)
- Solid tumor treatment
Introduction Of Koselugo 25mg Capsule
Koselugo 25mg Capsule is used to treat children aged 2 years and older with neurofibromatosis type 1 (NF1), a genetic condition that causes the growth of tumors on nerve tissues. It works by targeting a protein involved in tumor growth.
Koselugo 25mg Capsule can be taken with or without food. It should be taken exactly as prescribed by the doctor. It should be taken regularly and at the same time each day for the best outcomes. To maximize the benefits, follow all instructions carefully and get regular check-ups to monitor the progress of the treatment.
Common side effects of Koselugo 25mg Capsule include nausea, vomiting, diarrhea, abdominal pain, fatigue, musculoskeletal pain, fever, and rashes. For mild side effects, the doctor may recommend staying hydrated or resting when feeling fatigued. However, for severe or persistent symptoms, such as extreme stomach pain, yellowing of the skin or eyes, or difficulty breathing, seek immediate medical attention.
While on treatment with Koselugo 25mg Capsule, grapefruit or grapefruit juice should be avoided, as it can interfere with how the medication works. This medicine should be used cautiously in patients who have a history of liver or heart problems. Additionally, activities that may increase the risk of infections or injury should be avoided, as the medicine can sometimes weaken the immune system or make the patient more prone to bruising.
Benefits of Koselugo Capsule
In Treatment of Neurofibromatosis type 1 (NF1)
Koselugo 25mg Capsule is used to treat children aged 2 years and above with neurofibromatosis type 1 (NF1), particularly those with symptomatic, inoperable tumors. Koselugo 25mg Capsule helps slow tumor growth and reduce the size of tumors. This results in reduced pain, improved physical function, and decreased disfigurement caused by these benign growths. This improvement in tumor size and symptoms can improve mobility and reduce the need for invasive surgeries. When taken in the right dose and duration, Koselugo 25mg Capsule helps improve the overall quality of life for patients and allows them to engage more fully in daily activities with less discomfort.
Side effects of Koselugo Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Koselugo
- Headache
- Paronychia
- Itching
- Vomiting
- Rash
- Abdominal pain
- Diarrhea
- Nausea
- Dry skin
- Fatigue
- Musculoskeletal (bone, muscle or joint) pain
- Fever
- Stomatitis (Inflammation of the mouth)
How to use Koselugo Capsule
Take this medicine in the dose and duration as advised by your doctor. Koselugo 25mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Koselugo Capsule works
Koselugo 25mg Capsule works by blocking a protein called MEK, which is part of a system in the body that controls cell growth. In neurofibromatosis type 1 (NF1), this system can become too active because of a genetic change, causing tumors called plexiform neurofibromas to grow. By turning off MEK, Koselugo 25mg Capsule helps slow down or shrink these tumors, reducing symptoms like pain or difficulty moving, and improving the patient’s daily life.
Safety advice
Alcohol
Unsafe
It is not known whether it is safe to consume alcohol with Koselugo 25mg .
Pregnancy
Consult your doctor
Koselugo 25mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby.
Breast feeding
Consult your doctor
Information regarding the use of Koselugo 25mg during breastfeeding is not available.
Driving
Consult your doctor
Koselugo 25mg may cause side effects which could affect your ability to drive.
Kidney
Consult your doctor
Koselugo 25mg is safe to use in patients with kidney disease.
Liver
Consult your doctor
Koselugo 25mg should be used with caution in patients with liver disease. Dose adjustment of Koselugo 25mg Capsule may be needed.
Brand
Astrazeneca Pharma India LTD
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