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Actemra 80mg Injection
Uses of Actemra 80mg Injection
- Rheumatoid arthritis
- Giant cell arteritis (GCA)
- Polyarticular Juvenile Idiopathic Arthritis (pJIA)
- Systemic Juvenile Idiopathic Arthritis (sJIA)
- Cytokine release syndrome
Product Description
Introduction to Actemra 80mg Injection
Actemra 80mg injection contains an active component called tocilizumab. This medicine belongs to a group of monoclonal antibody (a protein made from specific immune cells). This is used in conditions such as moderate to severe active rheumatoid arthritis (RA) and who have inadequate response with other rheumatoid drugs, giant cell arteritis (disease in arteries), children with systemic juvenile idiopathic arthritis (sJIA), polyarticular juvenile idiopathic arthritis (pJIA) which result in the pain and swelling in one or more joints in children of 1 to 2 year and above.
Children with allergic reactions to ingredients and severe infections should consult their doctor before taking the medicine. Talk to your doctor immediately if you have any allergic reaction (difficulty with breathing, chest tightness rash, itching, hives, swelling lips, tongue, or face), infection (short- or long-term), tuberculosis, intestinal ulcers or diverticulitis (small bulging pouches developed in the digestive tract), liver disease, cancer, kidney function problems, and persistent headaches.
Inform your doctor if the Children have a history of macrophage activation syndrome (activation and uncontrolled proliferation of specific blood cells). The elderly are more likely to develop infections than the general population, so it is important to be cautious when treating them. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.
Therapeutic Effects of Actemra 80mg Injection
Actemra 80mg injection inhibits the function of a particular protein known as interleukin-6, which plays a role in the body’s inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.
Interaction of Actemra 80mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with actemra 80mg injection and can cause undesirable side effects.
More Information about Actemra 80mg Injection
- Protect from light and moisture
- Store at 2°C – 8°C
- Keep children away from the sight and reach of this medication.
How to consume Actemra 80mg Injection
Actemra 80mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advices for Actemra 80mg Injection
Pregnancy
Consult your healthcare provider if you plan to get pregnant. However, Actemra 80mg injection has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.
Breast Feeding
It is unknown whether actemra 80mg injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.
Lungs
It is unknown whether actemra 80mg injectionis safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Inform your physician about any underlying liver disorders before taking actemra 80mg injection, as this medication should be used cautiously in liver disease patients.
Alcohol
It is unknown whether actemra 80mg injection is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
Driving
Actemra 80mg injection may cause drowsiness in the patient while under medication. So, it is recommended to consult your doctor before handling vehicles and machinery.
Side Effects of Actemra 80mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face)
- Fever and chills
- Mouth or skin blisters
- Stomach ache
Common
- Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache)
- High blood fat (cholesterol) levels
- Injection site reactions.
- Lung infection (pneumonia)
- Shingles (herpes zoster)
- Cold sores (oral herpes simplex), blisters
- Eye infection (conjunctivitis)
- Headache, dizziness, high blood pressure
- Mouth ulceration, stomach pain
- Fluid retention (edema) in the lower legs, weight increase
- Cough, shortness of breath
- Low white blood cell counts (neutropenia, leucopenia)
- Abnormal liver function tests (increased transaminases)
- Increased bilirubin shown by blood tests
- Low fibrinogen levels in the blood (a protein involved in blood clotting)
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