Koselugo 10mg Capsule

Selumetinib

Uses of Koselugo 10mg Capsule

  • Melanoma treatment
  • Neurofibromatosis type 1 (NF1)
  • Solid tumor treatment

Introduction to Koselugo 10mg Capsule

Koselugo 10 mg Capsule contains an active component called Selumetinib. It is a medication used in the treatment of certain types of cancers, particularly melanoma (a type of skin cancer) and other solid tumors, including non-small cell lung cancer and ovarian cancer, especially in cases where there’s a specific genetic mutation that makes the cancer cells sensitive to MEK inhibitors. It may be prescribed for patients with advanced melanoma that has a specific genetic mutation, often BRAF-mutant melanoma. It has shown promise in treating plexiform neurofibromas, tumors associated with NF1, a genetic disorder that causes tumors to grow on nerves.

Individuals who have had a severe allergic reaction to Koselugo 10 mg Capsule or any of its components should not take this medication. It may cause harm to an unborn baby, so it is not recommended for use during pregnancy.  Patients with pre-existing heart conditions or a history of heart problems may need close monitoring or might not be suitable candidates for this medication. Older individuals, especially those over 65, may have an increased risk of certain side effects. Close monitoring for adverse reactions is typically recommended after taking this medication. The safety and efficacy of Koselugo 10 mg Capsule in children under specific ages may not be well-established.

Therapeutic Effects of Koselugo 10mg Capsule

Koselugo 10 mg Capsule is a medication that targets a specific cellular pathway called the MEK pathway, crucial for regulating cell growth. In cancers like melanoma and certain tumors, it blocks this pathway, disrupting signals that promote uncontrolled cell growth. By inhibiting this pathway, it slows down or halts the progression of cancer cells, reducing tumor growth and spread.


Interaction of Koselugo 10mg Capsule with other drugs

Inform the doctor about your medicines, including prescription, over the counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Koselugo 10 mg Capsule, reducing effectiveness by causing undesirable side effects.


More Information about Koselugo 10mg Capsule

  • Stored at controlled room temperature, between 20°C to 25°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Koselugo 10mg Capsule

Koselugo 10 mg Capsule is primarily administered orally, typically in the form of capsules. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.


Safety Advices for Koselugo 10mg Capsule

 

Pregnancy

It is not safe to take Koselugo 10 mg Capsule during pregnancy as it may cause harm to the unborn baby.

 

Breast Feeding

It is not safe to breastfeed while taking Koselugo 10 mg Capsule, as it may pass into breast milk and harm the infant.

 

Lungs

Consult your health care provider before taking  Koselugo 10 mg Capsule if you have lung diseases.

 

Liver

If you have a liver condition or are concerned about the safety of  Koselugo 10 mg Capsule, it is recommended to consult your healthcare provider for personalized advice.

 

Alcohol

There are no specific interactions between alcohol and Koselugo 10 mg Capsule, but alcohol consumption might exacerbate certain side effects such as dizziness or liver-related problems. It is advisable to consult a healthcare professional regarding alcohol consumption while on this medication.

 

Driving

Taking Koselugo 10 mg Capsule while driving is unsafe as it might cause dizziness or visual disturbances as side effects, which could affect the ability to drive or operate machinery.


Side Effects of Koselugo 10mg Capsule

Koselugo 10 mg Capsule causes some side effects like all medications, although not everyone will experience them.

Serious:

  • Heart problems
  • Eye problems
  • Interstitial lung disease (ILD)
  • Liver problems
  • Skin toxicities

Common:

  • Nausea and vomiting
  • Diarrhea
  • Fatigue
  • Skin rash
  • Swelling or fluid retention

Brand

Astrazeneca Pharma India LTD

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