Methostes 1000mg Injection

Introduction to Methostes 1000mg Injection

Methostes 1000mg Injection contains the active substance Methotrexate. It is an anti-metabolite and immunosuppressant drug. It treats certain types of cancer, such as acute lymphocytic leukemia (ALL), meningeal leukemia, non-Hodgkin’s lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also used to treat severe psoriasis in adults (a skin disease in which red, scaly patches form on some body areas). It is also indicated to treat rheumatoid arthritis in adults.

Do not use Methostes 1000mg Injection if you are allergic to methotrexate or any of the other ingredients of this medicine. Do not take this medicine if you have kidney or liver problems, blood disorders, weakened immune system, pregnancy, or breastfeeding. Inform your physician immediately if you experience any symptoms of spitting and coughing up blood, general muscle weakness, vision disturbance, changes in thinking, memory, and orientation problems. This medicine may impair fertility. Avoid getting pregnant during the treatment and for six months after the last dose.

Tell your doctor if you have a stomach ulcer, active infection, or mild kidney problems and about any recent vaccinations before starting the treatment. Methostes 1000mg Injection can cause serious side effects even with low doses; hence, regular follow-ups and routine laboratory tests will be necessary as a precaution. Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant.

Therapeutic Effects of Methostes 1000mg Injection

Methostes 1000mg Injection inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow, spread, and suppress the immune system in autoimmune diseases.

Interaction of Methostes 1000mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with Methostes 1000mg Injection and reduce their effectiveness by causing undesirable side effects.

More Information about Methostes 1000mg Injection

Store the Methostes 1000mg Injection below 25°C
Do not freeze
Protect the medicine from light and excessive moisture.
Keep the medicine out of reach of children and pets
If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment.

How to consume Methostes 1000mg Injection

Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this injection. Methostes 1000mg Injection is injected into a vein (intravenously) or into muscle (intramuscularly). Do not self-administer this medicine.

Safety Advices for Methostes 1000mg Injection

Pregnancy

Do not use Methostes 1000mg Injection during pregnancy because it can cause birth defects. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for six months after the last dose.

Breast Feeding

Breastfeeding is not recommended in patients taking Methostes 1000mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Lungs

Methostes 1000mg Injection should be cautiously used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

Methostes 1000mg Injection is contraindicated in patients with acute liver failure. Dose adjustments are necessary if you have liver problems. Inform your physician if you have any liver disease before initiating the therapy.

Alcohol

It is unsafe to drink alcohol while you take Methostes 1000mg Injection because it may cause damage to your liver.

Driving

Do not drive or operate heavy machinery if you experience any side effects, such as dizziness, drowsiness, or blurred vision.

Side Effects of Methostes 1000mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

Hairloss
Photosensitivity
Rash
Diarrhea, Nausea and Vomiting
Decreased WBC and platelet count
Dizziness
Tiredness, fever, and shivering
Blurred vision

Serious

Severe allergic reactions
Spitting or coughing blood
Chest pain
Weakness on one side of the body
Muscle weakness

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