Ontramab 440mg Injection

Trastuzumab

Uses of Ontramab 440mg Injection

Ontramab 440mg Injection is indicated for its use in the following conditions:

  • Advanced and metastatic breast cancer
  • Metastatic gastric cancer

Introduction to Ontramab 440mg Injection

Ontramab 440mg Injection consists of Trastuzumab as an active constituent which is indicated for its use in HER 2 breast cancer. In HER 2 positive patients, the breast cancer cells are mostly composed of HER2 proteins that cause rapid development of cancer tumor by serving as a signal to the cancerous. This medication is also used to treat metastatic gastric cancer with increased levels of HER2 proteins.

Her 2 positive breast cancer are most aggressive in nature. The targeted therapy for her 2 positive breast cancer works by selectively targeting the proteins that are responsible for the growth, development, and spread of cancer. Use effective birth control during the treatment and for at least 7 months after the final dose.

Ontramab 440mg Injection is not recommended for patients aged under 18, patients who have severe breathing problems or need oxygen treatment. It is necessary to let your physician know if you have any heart problems, breathlessness, or have ever had any other cancer treatment. Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this medication.

Therapeutic Effects of Ontramab 440mg Injection

The protein called HER2 (human epidermal growth factor receptor 2) is found in abundant amounts on the surface of certain cancer cells, where it stimulates cancer growth. Ontramab 440mg Injection selectively binds to HER2 and stops the growth of cancer cells.


Interaction of Ontramab 440mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Ontramab 440mg Injection and cause undesirable side effects.


More Information about Ontramab 440mg Injection

  • Keep Ontramab 440mg Injection out of sight and reach of children.
  • Store between 2˚C and 8˚C.

How to consume Ontramab 440mg Injection

  • Ontramab 440mg Injection shall either be administered before or after surgery.
  • It will be given as an Intravenous infusion for 90 minutes, if well tolerated it shall be administered within 30 minutes for the next doses.

Safety Advices for Ontramab 440mg Injection

 

Pregnancy

Discuss with your physician before taking this Ontramab 440mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take as it may cause to the unborn baby.

 

Breast Feeding

Avoid breastfeeding your baby while on the treatment with Ontramab 440mg Injection atleast for at least seven months after the final dose.

 

Lungs

Talk to your doctor if you have any lung conditions before starting treatment with Ontramab 440mg Injection.

 

Liver

You need to tell your physician if you have any liver disorders before starting Ontramab 440mg Injection as it requires dosage adjustment for severe liver impairment.

 

Alcohol

Consult your doctor to know if it is safe to consume alcohol while you are on treatment with Ontramab 440mg Injection.

 

Driving

Ontramab 440mg Injection can cause unusual tiredness and dizziness. Hence, it is advised to avoid driving or handling machinery during the treatment.


Side Effects of Ontramab 440mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

  • Heart Problems
  • Allergic reactions
  • Kidney problems
  • Breathing difficulties

Common

  • Fever
  • Visual disturbances
  • Nose bleeds or runny nose
  • Hair loss
  • Dizziness
  • Nail disorders
  • Weight loss
  • Loss of appetite
  • Bruising
  • Dry mouth
  • Liver  inflammation
  • Muscle pain
  • Asthma/ lung disorders

Brand

Celon Laboratories LTD

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