Pangraf 0.1% Ointment

Introduction to Pangraf 0.1% Ointment

Pangraf 0.1% Ointment contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. It is used to treat moderate to severe atopic dermatitis (eczema) in adults who cannot use other medications for their condition or whose eczema has not responded to other medications. It suppresses the immune system from producing substances that may develop eczema.

Do not take this Pangraf 0.1% Ointment if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver failure, skin problems or skin cancer, or a weakened immune system. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.

Limit exposure to sunlight and UV light while consuming Pangraf 0.1% Ointment by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. Do not apply this ointment to the infected areas if you have infected lesions. If you notice any change in the appearance of your skin, consult your physician immediately. This medicine is not approved for children younger than 16 years of age.

Therapeutic Effects of Pangraf 0.1% Ointment

Pangraf 0.1% Ointment provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response. It works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response.

Interaction of Pangraf 0.1% Ointment with other drugs

Inform your healthcare provider about all the medicines that you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Pangraf 0.1% Ointment and reduce its effectiveness by causing undesirable side effects. Avoid grapefruit or grapefruit juice while taking this medicine.

More Information about Pangraf 0.1% Ointment

Store Pangraf 0.1% Ointment at (25°C)
keep the capsule away from the reach of children and pets.
If you forget to apply the ointment at the scheduled time, do it as soon as you remember. If it is almost time for the application, skip the missed dose.
Do not apply more quantity than advised.

How to consume Pangraf 0.1% Ointment

This medicine is only for topical use. Always use Pangraf 0.1% Ointment exactly as advised by your doctor. Apply the ointment as a thin layer to the affected areas of your skin. Avoid using the ointment inside your nose, mouth, or eyes. Before using the ointment, be sure your skin is completely dry. Your doctor will say the exact amount and time you should use this ointment. If you accidentally swallowed the ointment, contact your physician immediately and seek medical advice.

Safety Advices for Pangraf 0.1% Ointment

Pregnancy

Based on animal studies, Pangraf 0.1% Ointment can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant before initiating the treatment.

Breast Feeding

Do not consume Pangraf 0.1% Ointment if you are breastfeeding because this medicine is excreted into breast milk and may cause harmful effects on the body.

Lungs

It is unknown whether Pangraf 0.1% Ointment can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

Pangraf 0.1% Ointment should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver problems before initiating the therapy.

Alcohol

It is unsafe to consume alcohol when taking Pangraf 0.1% Ointment because it may cause the skin or face to become flushed or red and feel hot.

Driving

It is unknown whether Pangraf 0.1% Ointment can impair the ability to drive. Consult your doctor for more advise.

Side Effects of Pangraf 0.1% Ointment

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

Burning sensation and itching
Redness, feeling or warmth
Pain
Increased skin sensitivity to hot and cold
Skin tingling
Rash

Serious

Acne
Facial redness
Eye infections
Lentigo (flat brown spots on the skin)
Cold sores
Swelling of the hands, arms, feet, ankles, or lower legs

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