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Tysabri 300mg Injection
Uses of Tysabri 300mg Injection
Tysabri 300mg injection is used to treat the following:
- Multiple sclerosis (MS)
- Crohn’s disease.
Product Description
Introduction to Tysabri 300mg Injection
Tysabri 300mg injection contains an active component such as Natalizumab. This medication is a monoclonal antibody medication used to treat multiple sclerosis (MS) and Crohn’s disease. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system, causing communication problems between the brain and the rest of the body. Crohn’s disease is a chronic inflammatory condition affecting the gastrointestinal tract. This medication-targeted mechanism of action reduces inflammation by blocking specific immune cell movement, thereby mitigating potential damage to the central nervous system in MS or reducing inflammation in the gut in Crohn’s disease. By effectively managing disease activity, Tysabri 300mg injection can improve patients’ overall quality of life by reducing symptoms, decreasing the frequency of relapses, and potentially delaying disability progression.
Tysabri 300mg injection can cause hypersensitivity reactions in some individuals. Patients with a history of hypersensitivity to this medicine or its components should avoid its use, and individuals at higher risk need screening. This medication is contraindicated in patients with a history of progressive multifocal leukoencephalopathy (PML) or who are positive for the JC virus, as they are at a higher risk of developing PML during treatment. It should not be used in patients with active infections, especially serious or opportunistic infections. Its safety and effectiveness in pediatric patients (children and adolescents) have not been fully established. Therefore, its use in this population is generally not recommended.
Therapeutic Effects of Tysabri 300mg Injection
Tysabri 300mg injection is a monoclonal antibody that works by targeting a protein called α4-integrin on certain immune cells. By binding to α4-integrin, it prevents these immune cells from crossing the blood-brain barrier in multiple sclerosis or migrating into the gut lining in Crohn’s disease. This action reduces inflammation and helps protect the central nervous system in MS, leading to fewer relapses and slowed disease progression. Overall, its mechanism of action modulates the immune response, providing therapeutic benefits in treating multiple sclerosis and Crohn’s disease.
Interaction of Tysabri 300mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tysabri 300mg injection, reducing effectiveness by causing undesirable side effects.
More Information about Tysabri 300mg Injection
- Store at room temperature, between 2°C to 8°C (36°F to 46°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Tysabri 300mg Injection
Tysabri 300mg injection should be taken exactly as prescribed by a healthcare professional. The route of administration for this medication is intravenous (IV) infusion. The medication is delivered directly into the bloodstream through a vein. It is not available in oral form or as a subcutaneous injection.
Safety Advices for Tysabri 300mg Injection
Pregnancy
Pregnant women or those planning to become pregnant should discuss all potential risks and benefits of using Tysabri 300mg injection with their healthcare provider. They will assess the risks and benefits of continuing the medication during pregnancy and discuss alternative treatments if necessary.
Breast Feeding
The safety of Tysabri 300mg injection during breastfeeding is not fully established, and the healthcare provider will provide personalized advice to make an informed decision regarding the use of the medication during this period, considering the well-being of both the mother and the baby.
Lungs
Patients taking Tysabri 300mg injection should promptly report any respiratory symptoms to their healthcare provider and adhere to prescribed treatments to manage their underlying condition effectively.
Liver
If you have liver-related medical conditions, such as liver disease or liver dysfunction, it is crucial to inform your healthcare provider about your condition before starting Tysabri 300mg injection or any other medication.
Alcohol
Limit alcohol consumption and consult your healthcare provider for personalized advice regarding alcohol use while taking Tysabri 300mg injection.
Driving
During treatment with Tysabri 300mg injection, patients should exercise caution when driving, as the medication may cause dizziness, fatigue, or other central nervous system-related side effects.
Side Effects of Tysabri 300mg Injection
Tysabri 300mg injection causes some side effects like all medications, although not everyone will experience them.
Serious:
- Progressive multifocal leukoencephalopathy (PML)
- Infusion reactions
- Liver damage
- Infections
- Hypersensitivity
Common:
- Headache
- Fatigue
- Nausea
- Upper respiratory tract infections (common cold)
- Urinary tract infections
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