Tasigna 150mg Capsule

Introduction to Tasigna 150mg Capsule

Tasigna 150mg capsule is an antineoplastic drug with an active ingredient called Nilotinib. It belongs to the medication class known as tyrosine kinase inhibitors. This medicine is used to treat a type of leukemia called Philadelphia chromosome-positive chronic myeloid leukemia (Ph-positive CML), a blood cancer with abnormal production of WBC. In adult and pediatric patients, it is used in a patient who is newly diagnosed with Chronic Myeloid Leukemia (CML) and those facing side effects from previous treatment. Additionally, it is also used in patients with no longer respond to the previous treatment including Imatinib.

Do not take this medicine if you are allergic to Nilotinib or the other ingredients of this medicine. Notify your doctor if you have or had a history of heart conditions (heart attack, abnormal electric signal), chest pain, brain stroke, or claudication ( condition of blood flow in the leg). Inform your doctor if you have liver or pancreas disorder, or suffering from a lack of potassium or magnesium. You need to tell your doctor about all the medications especially if you take medicine to lower your blood cholesterol. Tell your doctor about your underlying condition especially inform about if you have or ever had a hepatitis B infection; this medicine can activate HPV again which can be fatal in some cases. Avoid consuming grapefruit or grapefruit juice. Inform your doctor if you are intolerant to some sugar, as Tasigna 150mg contains lactose.

During the treatment, your doctor may conduct a regular blood test to monitor the liver and pancreas function, and the number of blood cells (WBC, RBC, platelets). Also to monitor the heart condition (prolongation of the QT interval), electrolytes in the body, and the level of sugar and fats to check how Tasigna 150mg is tolerated. Inform your doctor if you are pregnant or planning to get pregnant or breastfeeding. Use effective birth control during the treatment with this medicine.

Therapeutic Effects of Tasigna 150mg Capsule

BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Tasigna 150mg disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.

Interaction of Tasigna 150mg Capsule with other drugs

Inform your healthcare professional about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, and herbal products. Certain medications such as antiarrhythmics, chloroquine, Titonavir, Carbamazepine, or any other drugs, interacting with Tasigna 150mg may reduce effectiveness by causing undesirable side effects.

More Information about Tasigna 150mg Capsule

Keep this medicine out of the sight and reach of children and pets
Do not store above 30°C
Keep it in its original packaging in order to protect it from light and moisture.
During treatment, you may also have a high level of liver enzymes, urea, or insulin. Contact your doctor immediately if you experience any unusual symptoms.

How to consume Tasigna 150mg Capsule

Take Tasigna 150mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking this medicine unless your doctor advises you to stop.

Safety Advices for Tasigna 150mg Capsule

Pregnancy

Tasigna 150mg is unsafe to use during pregnancy unless it is necessary. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment; your doctor will tell you whether you can take this medicine during your pregnancy.

Breast Feeding

Taking Tasigna 150mg while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.

Lungs

It is unknown if patients with lung conditions can consume Tasigna 150mg or not. So, before beginning the treatment, consult your doctor if you have any lung conditions. Consult your doctor if you experience symptoms like difficulty in breathing, wheezing, or any other lung-related condition while taking this medicine.

Liver

Inform your physician if you have liver problems because Tasigna 150mg should be used cautiously with this condition. Before starting treatment, your physician conducts the liver function test.

Alcohol

It is unknown whether consuming alcohol while taking a Tasigna 150mg capsule is safe. Please speak with your physician.

Driving

While taking Tasigna 150mg, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.

Side Effects of Tasigna 150mg Capsule

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

Sudden weight gain
Swelling in hands, feet, ankles, or face
Chest pain
Blood pressure (high and low)
Discoloration of tongue, lips, or skin (blue)
Abnormal heart (irregular heartbeat)
Hair loss
Vision problem
Stomach pain, vomiting of blood, blood in stools.
Yellowing of the skin, eyes, and dark urine.
High blood sugar levels.
Sensitivity to light

Common:

Nausea, vomiting, diarrhea.
Headache, muscle pain, stomach pain.
Hair loss.
Tiredness.
Constipation.
Slowing of growth in children.
Pneumonia.
Loss of appetite.
Sleeplessness, depression, and anxiety.
Stomach discomforts like bloating and flatulence after meals
musculoskeletal pain

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