Shilstine 50mg Injection

Uses of Shilstine 50mg Injection

  • Methotrexate overdose and toxicity
  • Prevent the harmful effects of methotrexate or similar medications
  • Colorectal cancer
  • Anemia

Introduction to Shilstine 50mg Injection

Shilstine 50mg Injection contains the active substance Leucovorin calcium which is chemically related to a vitamin called folic acid. It belongs to the class folic acid analogs. It is used to prevent the harmful effects of methotrexate medicine when treating certain types of cancer. It is also used to treat people who have accidentally overdosed on methotrexate medicine or medications that belong to a similar class. It is also used with other anticancer medications to treat colorectal cancer (cancer that begins in the colon or rectum). Other uses include treating anemia caused by low levels of folic acid in the body.

Do not take Shilstine 50mg Injection if you are allergic to Leucovorin calcium, calcium folinate, or any other ingredients of this medicine if you have certain types of anemia (pernicious anemia or megaloblastic anemia) where vitamin B12 is deficient. Before initiating the treatment, inform your physician if you have anemia, kidney, heart, or liver problems. Inform your physician if you are using any medications for treating seizures. Notify your physician if you face any symptoms of wheezing or trouble breathing, skin rash, itching or hives, or swelling in the lips, face, or tongue.

Therapeutic Effects of Shilstine 50mg Injection

Shilstine 50mg Injection counteracts the therapeutic effects of folic acid antagonists such as methotrexate and similar medications by inhibiting the dihydrofolate reductase enzyme. It treats anemia by supplying the folic acid needed for red blood cell formation. It treats colorectal cancer by enhancing the therapeutic effects of another anticancer medication called 5-fluorouracil.


Interaction of Shilstine 50mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Shilstine 50mg Injection and reduce its effectiveness by causing undesirable side effects. Especially inform your physician if you are taking medications for seizures.


More Information about Shilstine 50mg Injection

  • Store Shilstine 50mg Injection in a refrigerator at 2° to 8°C
  • Keep the injection away from the reach of children and pets.
  • If you forgot your dosing schedule, inform your healthcare professional immediately and reschedule the dosing

How to consume Shilstine 50mg Injection

A trained physician or nurse in cancer chemotherapy will administer the drug to you.  Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. The medicine is administered either intravenously (into your vein) or intramuscularly (into your muscle) based on your disease condition.


Safety Advices for Shilstine 50mg Injection

 

Pregnancy

There is a limited number of studies on the safety of Shilstine 50mg Injection during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

 

Breast Feeding

Limited information is available on Shilstine 50mg Injection safety during breastfeeding. Inform your physician if you are planning to breastfeed.

 

Lungs

It is unknown whether Shilstine 50mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

 

Liver

It is unknown whether Shilstine 50mg Injection can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.

 

Alcohol

It is unknown whether it is safe to consume alcohol when taking Shilstine 50mg Injection. Consult your doctor for more advice.

 

Driving

It does not affect the ability to drive or operate heavy machinery after taking Shilstine 50mg Injection.


Side Effects of Shilstine 50mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

 Common

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammmed and sore mouth
  • Tiredness

Serious

  • Allergic reactions

Brand

Shilpa Medicare LTD

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