Rituxem 500mg Injection
Uses of Rituxem 500mg Injection
- Non-hodgkin’s lymphoma (NHL)
- Chronic lymphocytic leukemia (CLL)
- Rheumatoid Arthritis
- Granulomatosis with polyangiitis or microscopic polyangiitis
- Pemphigus vulgaris
Introduction Of Rituxem 500mg Injection
Rituxem 500mg Injection contains the active constituent rituximab. It is used for several different disease conditions in adults. It is used alone or with other medications to treat non-hodgkin’s lymphoma and chronic lymphocytic leukemia . It is also indicated to treat moderate-to-severe rheumatoid arthritis (a type of disease where the immune system attacks the leukapheresis body cells of its own joints) in combination with methotrexate in adults.
Rituxem 500mg injection belongs to the class of medications called anti-CD20 monoclonal antibodies. Do not take this injection if you are allergic to rituximab or any other ingredients of this medicine, have a weak immune system, or have any severe active infection. Inform your physician if you have heart disease, heart failure, or breathing problems before initiating the treatment.
Common side effects of Rituxem 500mg injection include infection of the blood, reduced red blood cells, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and low or high blood pressure. Use effective contraceptives during the treatment and 12 months after the last dose if you can get pregnant.
Therapeutic Effects of Rituxem 500mg Injection
Rituxem 500mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes (a type of white blood cells). When this medicine binds to the B-cell, it induces cell death in NHL and CLL. The binding action blocks cell activation and growth and cause anticancer effects. It inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.
Interaction of Rituxem 500mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. In particular, tell your doctor if you are taking medicines for blood pressure or other heart conditions. Certain medications may interact with Rituxem 500mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Rituxem 500mg Injection
- Store Rituxem 500mg injection in the refrigerator (2°C to 8°C)
- Do not freeze
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Rituxem 500mg Injection
It should only be administered by a trained doctor or nurse. Do not self-administer the injection. Before giving Rituxem 500mg injection, you will be given other medications (pre-medication) to reduce the possible side effects.
Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for any unwanted side effects.
Safety Advices for Rituxem 500mg Injection
Pregnancy
Consult your doctor
Rituxem is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Breast Feeding
Consult your doctor
Breastfeeding is not recommended in patients taking Rituxem 500mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
Consult your doctor
It is unknown whether Rituxem can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Consult your doctor
Whether Rituxem can be used in patients with liver impairment is unknown.
Alcohol
Unsafe
Consuming alcohol may affect the effectiveness of Rituxem.
Driving
Consult your doctor
Caution is required while driving and operating machinery when you take Rituxem because it may cause dizziness, sleepiness, tiredness, and risk of falling.
Side Effects of Rituxem 500mg Injection
Common
- Swelling in the face and body
- Diarrhea and nausea
- Itchy skin
- Anemia
- Muscle spasm
Serious
- Increased or decreased blood pressure
- Chest pain
- Hypersensitivity reactions
- Hepatitis B viral infection
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