Plegridy 125mcg Injection

Pegylated Interferon Beta-1a

Uses of Plegridy 125mcg Injection

  • Multiple sclerosis (MS) treatment
  • Relapse rate reduction
  • Delaying disability progression
  • Inflammation and immune modulation
  • MRI lesion reduction
  • Alternative disease-modifying therapy (DMT)

Introduction to Plegridy 125mcg Injection

Plegridy 125mcg injection contains active components as Pegylated Interferon Beta-1A. It  is a medication used to treat multiple sclerosis (MS). Multiple sclerosis is a chronic autoimmune disease of the central nervous system characterized by inflammation, demyelination, and a wide range of neurological symptoms. One of the primary benefits of this medication is its ability to reduce the frequency of relapses in individuals with relapsing forms of MS. This can lead to a more stable disease course.: Modulating the immune response and reducing inflammation may slow down the progression of disability in people with MS. This can help individuals maintain a higher level of functioning for a longer period.

Individuals who have a known hypersensitivity or allergy to Plegridy 125mcg injection or any of its components should not use this medication. Suppose a patient has a history of severe depression, significant mood disorders, or suicidal ideation. In that case, the use of this medication should be carefully considered as it can have neuropsychiatric side effects. It can affect liver function, and individuals with severe liver disease or liver dysfunction should not use this medication. Although it primarily undergoes hepatic metabolism (in the liver), it is also partially excreted through the kidneys. Patients with severe renal impairment may require dose adjustments or alternative treatments. The safety and effectiveness of Plegridy 125mcg injection in pediatric patients have not been established, and it is generally not recommended for use in children.

Therapeutic Effects of Plegridy 125mcg Injection

Plegridy 125mcg injection works by modulating the immune system’s response, reducing inflammation, and shifting it towards an anti-inflammatory state. This mechanism helps decrease immune cell activation, lowers pro-inflammatory molecule production, and inhibits immune cell migration into the central nervous system. As a result, it reduces the frequency of relapses and delays disability progression in individuals with multiple sclerosis (MS).


Interaction of Plegridy 125mcg Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with  Plegridy 125mcg injection, reducing effectiveness by causing undesirable side effects.


More Information about Plegridy 125mcg Injection

  • Stored at room temperature from 2°C to 8°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Plegridy 125mcg Injection

Plegridy 125mcg injection is typically administered  via subcutaneous injection. It is essential to follow your healthcare provider’s guidance and any instructions provided with the medication.


Safety Advices for Plegridy 125mcg Injection

 

Pregnancy

There is limited information on the safety of Plegridy 125mcg injection in pregnant women. It is, therefore, important to talk to your doctor before using it if you are pregnant.

 

Breast Feeding

It is not known whether Plegridy 125mcg injection passes into breast milk. It is, therefore, important to talk to your doctor before using it if you are breastfeeding.

 

Lungs

Plegridy 125mcg injection does not directly affect lung function. However, individuals with lung issues should consult a healthcare provider before using it.

 

Liver

Plegridy 125mcg injection can affect liver function, so it is important to consult a healthcare provider before taking this medication.

 

Alcohol

The interaction between alcohol and Plegridy 125mcg injection is not well-documented. However, alcohol can have its own effects on the liver and the central nervous system, and it’s advisable to consume alcohol in moderation or as your healthcare provider recommends.

 

Driving

Plegridy 125mcg injection does do not cause any side effects that would affect your driving ability. However, if you experience dizziness or other unusual side effects, it’s best to consult your healthcare provider.


Side Effects of Plegridy 125mcg Injection

Plegridy 125mcg injection causes some side effects like all medications, although not everyone will experience them.

Serious

  • Liver problems
  • Myelosuppression
  • Neuropsychiatric effects
  • Allergic reactions
  • Anaphylaxis
  • Cardiovascular issues
  • Seizures
  • Autoimmune disorders

Common

  • Flu-like symptoms
  • Injection site reactions
  • Headache
  • Nausea
  • Fatigue
  • Mood changes

Brand

Eisai Phamaceutical PVT LTD

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