Introduction to Pemnat 100mg Injection
Pemnat 100mg injection is an anticancer medicine containing the active ingredient Pemetrexed. It belongs to the medication class known as an antifolate agent. It is used to treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This medicine is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to limit the side effects.
Blood tests will be taken before each infusion to determine whether your kidney and liver functions are adequate and whether you have enough blood cells to receive this medicine. Before starting treatment with Pemnat 100mg injection, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems, heart disorders, or fluid accumulation in the lungs. Report to your doctor if you recently had or currently having radiotherapy or any vaccination before taking this medication.
Inform your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during the treatment and at least six months after the last dose of Pemnat 100mg injection. In men, it is recommended not to father a child during and up to 3 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. This medication is not recommended for adolescents and children under 18 years of age.
Therapeutic Effects of Pemnat 100mg Injection
Pemnat 100mg inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.
Interaction of Pemnat 100mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as may interact with Pemnat 100mg and reduce effectiveness by causing undesirable side effects.
More Information about Pemnat 100mg Injection
- Keep the tablets away from light and moisture.
- Store refrigerated at 2°C to 8°C.
- Keep the tablets out of the reach of children and animals.
How to consume Pemnat 100mg Injection
Pemnat 100mginjection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices for Pemnat 100mg Injection
Pregnancy
Do not take Pemnat 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.
Breast Feeding
It is unsafe to breastfeed while taking Pemnat 100mg because it can cause toxicity to the baby. If you are breastfeeding a baby, it has to be discontinued. Please consult your physician for more advice.
Lungs
Consult your doctor if you experience any symptoms like; shortness of breath, blockage, or inflammation in the lining of the lung while taking Pemnat 100mg.
Liver
Inform your physician about any underlying liver disorders before taking Pemnat 100mg, as this medication should be used with caution in liver disease patients.
Alcohol
It is unknown whether consuming alcohol while taking a Pemnat 100mg injection is safe. Please speak with your physician.
Driving
While taking Pemnat 100mg, driving or using machines is unsafe because it may cause nausea, fatigue, vomiting, etc. Talk to your doctor for more information.
Side Effects of Pemnat 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Blood infection
- Severe allergic reaction
- Breathlessness, intense chest pain or cough with bloody sputum
- Reduced neutrophil granulocytes (white blood cells)
- Kidney failure
- Pharyngitis (a sore throat)
- Abnormal liver function
Common
- Fatigue
- Nausea, vomiting, diarrhea
- Redness, swelling or sores in the mouth
- Loss of appetite, sensation
- Reduced hemoglobin level
- Increased skin pigmentation
- Watery and inflamed eyes, taste change
- Fever
- Muscle weakness
- Dehydration
- Constipation
- Skin rash
- Hair loss
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