Lupiximab 500mg Injection

Introduction Of Lupiximab 500mg Injection

Lupiximab 500mg Injection contains the active constituent rituximab. It is used for several different disease conditions in adults. It is used alone or with other medications to treat non-hodgkin’s lymphoma and chronic lymphocytic leukemia. It is also indicated to treat moderate-to-severe rheumatoid arthritis in combination with methotrexate in adults. Other uses include granulomatosis with polyangiitis or microscopic polyangiitis in adults and children 2 years of age and older.

Lupiximab 500mg injection belongs to the class of medications called anti-CD20 monoclonal antibodies. Do not take this injection if you are allergic to rituximab or any other ingredients of this medicine, have a weak immune system, or have any severe active infection. Inform your physician if you have heart disease, heart failure, or breathing problems before initiating the treatment. Talk with your doctor if you have ever had a hepatitis B infection because the infection may reactivate again in a few cases and can be severe sometimes.

Common side effects of Lupiximab 500mg injection include infection of the blood, reduced red blood cells, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and low or high blood pressure. Use effective contraceptives during the treatment and 12 months after the last dose if you can get pregnant.

This medicine may cause severe infusion reactions during or within 24 hours after administration. Inform your physician or healthcare professional if you face any infusion reactions, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling.

Therapeutic Effects of Lupiximab 500mg Injection

Lupiximab 500mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes (a type of white blood cells). When this medicine binds to the B-cell, it induces cell death in NHL and CLL. The binding action blocks cell activation and growth and cause anticancer effects. It inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.

Interaction of Lupiximab 500mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. In particular, tell your doctor if you are taking medicines for blood pressure or other heart conditions. Certain medications may interact with Lupiximab 500mg injection and reduce its effectiveness by causing undesirable side effects.

More Information about Lupiximab 500mg Injection

Store Lupiximab 500mg injection in the refrigerator (2°C to 8°C)
Do not freeze
keep the injection away from the reach of children and pets.
If you have missed any dosing appointments, inform your doctor and schedule immediately.

How to consume Lupiximab 500mg Injection

It should only be administered by a trained doctor or nurse. Do not self-administer the injection. Before giving Lupiximab 500mg injection, you will be given other medications (pre-medication) to reduce the possible side effects. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for any unwanted side effects.

Safety Advices for Lupiximab 500mg Injection

Pregnancy

Consult your doctor

Lupiximab 500mg is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Breast Feeding

Consult your doctor

Breastfeeding is not recommended in patients taking Lupiximab 500mg because the medicine passes into the breast milk in small amounts and may harm your baby.

Lungs

Consult your doctor

It is unknown whether Lupiximab 500mg can be used in patients with lung disorders.

Liver

Consult your doctor

Whether Lupiximab 500mg can be used in patients with liver impairment is unknown. Consult your doctor if you have or ever had liver disease or hepatitis B infection before starting the treatment.

Alcohol

Unsafe

Consuming alcohol may affect the effectiveness of Lupiximab 500mg.

Driving

Consult your doctor

Caution is required while driving and operating machinery when you take Lupiximab 500mg because it may cause dizziness, sleepiness, tiredness, and risk of falling.

Side Effects of Lupiximab 500mg Injection

Common

Swelling in the face and body
Diarrhea and nausea
Itchy skin
Anemia
Muscle spasm
Headache
Urinary tract infection
Fever, chills, and shivering
Inflammation of nasal cavities
Cough, sore throat
Loss of hair

Serious

Increased or decreased blood pressure
Chest pain
Hypersensitivity reactions
Hepatitis B viral infection
Memory loss, trouble thinking, difficulty in walking

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