Introduction to Kerendia 20mg Tablet
Kerendia 20mg Tablet is a medication containing an active component called Finerenone. It falls under the category of nonsteroidal mineralocorticoid receptor antagonists (MRAs). Its purpose is to address conditions associated with imbalanced levels of mineralocorticoid hormones, specifically aldosterone, within the body. The primary usage of this medication is for the treatment of chronic kidney disease (CKD) in individuals diagnosed with type 2 diabetes. It aids in lowering the likelihood of kidney disease advancement and also mitigates the risk of cardiovascular incidents, such as heart failure, in these patients.
Kerendia 20mg Tablet should not be used in individuals with known hypersensitivity or allergy to the drug or its components. It can increase the potassium levels in the blood. It should be used cautiously or avoided in patients with hyperkalemia or those already taking medications that can increase potassium levels (such as potassium-sparing diuretics or potassium supplements). This medication can affect the balance of electrolytes in the body. Monitoring potassium, sodium, and other electrolyte levels may be necessary during treatment. Kerendia 20mg Tablet may affect blood glucose levels, especially in patients with diabetes. If a person is undergoing surgery, it is important to inform the healthcare team about using Kerendia 20mg Tablet, as it may need to be temporarily discontinued before the procedure.
Therapeutic Effects of Kerendia 20mg Tablet
Kerendia 20mg is a selective nonsteroidal mineralocorticoid receptor antagonist (MRA) that blocks the effects of aldosterone, a hormone involved in fluid balance and blood pressure regulation. Inhibiting mineralocorticoid receptors reduces sodium and water retention, prevents potassium excretion, and provides therapeutic benefits in chronic kidney disease, including slowing disease progression, reducing cardiovascular risk, and controlling blood pressure.
Interaction of Kerendia 20mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Kerendia 20mg Tablet and reduce their effectiveness by causing undesirable side effects.
More Information about Kerendia 20mg Tablet
- Store at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- Take only a partial dose to compensate for a forgotten dose.
How to consume Kerendia 20mg Tablet
To use Kerendia 20mg Tablet, follow the prescribed dosage and instructions provided by your healthcare provider. Take the medications as directed, usually orally, with or without food. Do not skip doses or stop taking them without consulting your healthcare provider. Consult your healthcare provider or pharmacist for guidance if you have any questions or concerns.
Safety Advices for Kerendia 20mg Tablet
Pregnancy
Kerendia 20mg Tablet may cause harm to an unborn baby. Inform your doctor if you are pregnant or planning to get pregnant before taking it. The doctor will explain the potential risks and benefits.
Breast Feeding
Breastfeeding is not recommended along with the treatment of Kerendia 20mg Tablet.
Lungs
Kerendia 20mg Tablet is contraindicated for severe liver impairment. Prior liver conditions or concerns should be communicated to the healthcare provider before starting it. For mild to moderate liver impairment, caution with potential dose adjustments and regular liver function monitoring is advised.
Liver
It is important to discuss your specific lung condition with your healthcare provider, as they can provide personalized advice based on your medical history and individual needs.
Alcohol
It is unsafe to drink alcohol while taking Kerendia 20mg Tablet. It may reduce the drug’s effectiveness and can cause toxic side effects.
Driving
Kerendia 20mg Tablet can cause dizziness. It is recommended to avoid driving and operating heavy machinery during the treatment.
Side Effects of Kerendia 20mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (e.g., rash, itching, swelling, severe dizziness, difficulty breathing)
- Worsening of kidney function or acute kidney injury
- Liver problems (e.g., jaundice, dark urine, abdominal pain)
- Severe hyperkalemia (symptoms can include muscle weakness, irregular heartbeat, and palpitations)
- Hypotension leading to fainting or loss of consciousness
Common
- Hyperkalemia (high levels of potassium in the blood)
- Diarrhea
- Dizziness
- Fatigue
- Headache
- Nausea
- Hypotension (low blood pressure)
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