Introduction to Bonitar 100mg Tablet
Bonitar 100mg Tablet contains the active ingredient bosutinib. It belongs to the group of medications called Tyrosine kinase inhibitors. It is indicated to treat adult patients with a type of leukemia known as Philadelphia chromosome-positive (Ph-positive) Chronic Myeloid Leukaemia (CML) who have been newly diagnosed or for whom earlier CML treatments have either failed or have not worked or are not suitable. Philadelphia chromosome-positive chronic myelogenous leukemia is a blood cancer in which the body produces too many of a specific kind of white blood cell called granulocytes.
Low white blood cell count (leukopenia), headache, shortness of breath, joint pain, dizziness, cough, back pain, decreased appetite, respiratory tract infection, raised blood pressure, ringing in the ears (tinnitus), itching, acne, dehydration, taste change, sensitivity to light and fluid on lungs are the common side effects of Bonitar 100mg Tablet. Inform your doctor if any of these symptoms disturb you or persist.
Inform your physician if you are allergic to Bonitar 100mg Tablet or its ingredients. Before taking this medication, report to your doctor if you have heart problems, bleeding problems, kidney and liver disorders, infection, or diarrhea. It is not recommended for children under the age of 18. Limit your time outside and use sunscreen if you must go outside, as this medicine can make you more sensitive to the sun or UV rays.
Therapeutic Effects of Bonitar 100mg Tablet
Bonitar 100mg Tablet works by inhibiting the activity of an enzyme called Bcr-Abl kinase that promotes the growth and spread of blood cancer (Ph+ CML). This helps to slow or stop the growth and spread of cancer cells.
Interaction of Bonitar 100mg Tablet with other drugs
Inform your doctor about any medications you are taking or have taken before the treatment.
More Information about Bonitar 100mg Tablet
- Keep Bonitar 100mg Tablet out of sight and reach of children.
- Store between 20° to 25°C.
How to consume Bonitar 100mg Tablet
Take Bonitar 100mg in the dose and duration prescribed by your doctor. Take this medicine once a day with food. Swallow it whole and avoid breaking or crushing the tablet. Do not handle or touch the broken tablets.
Safety Advices for Bonitar 100mg Tablet
Pregnancy
Unsafe
Bonitar 100mg is unsafe to use during pregnancy as it could cause potential harm to a developing baby. Consult the doctor before taking this medicine, and it will be given to you if clearly needed. Use effective birth control during and for 30 days (one month) after the last dose.
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking Bonitar 100mg, as it is not known whether it passes into the breast milk and harms your baby. Consult the doctor before taking this medication.
Lungs
Consult your doctor
Inform your doctor if you have any lung conditions before starting treatment with Bonitar 100mg.
Liver
Consult your doctor
Tell your doctor if you have a history of liver problems, including hepatitis, before taking Bonitar 100mg. Your doctor will perform blood tests to evaluate your liver function.
Alcohol
Consult your doctor
Drinking a small amount of alcohol does not affect the safety or usefulness of Bonitar 100mg. As a precautionary measure, limit or avoid alcohol with this medication.
Driving
Unsafe
Taking Bonitar 100mg can cause dizziness, blurred vision, or unusual tiredness. Do not drive if you feel unwell.
Side Effects of Bonitar 100mg
Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them.
Serious:
- Blood disorders (bleeding, fever, bruising)
- Stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea)
- Hepatitis B reactivation
- Severe skin reactions
- Liver problems (yellowing of white part of eyes and skin, tea-colored urine)
- Heart problems (loss of consciousness, irregular heartbeat)
Common:
- Low white blood cell count (leukopenia)
- Headache, dizziness
- Cough, shortness of breath
- Joint pain, back pain
- Decreased appetite
- Respiratory tract infection
- Increase in blood pressure
- Ringing in the ears (tinnitus)
- Itching, acne
- Dehydration
- Taste change
- Sensitivity to light
- Fluid on lungs
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