Introduction Of Azishil 100mg Injection
Azishil 100mg Injection is used for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant. In Myelodysplastic Syndrome, the bone marrow does not produce healthy blood cells due to its lack of function. Acute Myeloid Leukemia is a type of bone marrow cancer that is caused by the release of incompletely formed blood cells into the bloodstream.
Do not take Azishil 100mg injection if you are allergic to any of the other ingredients in the drug. Inform your physician about your medical and medication history before initiating the treatment. Tell your physician if you are pregnant, breastfeeding, or planning to get pregnant before taking this medicine.
Therapeutic Effects of Azishil 100mg Injection
In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azishil 100mg injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.
Interaction of Azishil 100mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Azishil 100mg Injection and reduce their effectiveness by causing undesirable side effects.
More Information about Azishil 100mg Injection
- Store the medicine below 30℃.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets.
How to consume Azishil 100mg Injection
Take Azishil injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight and general condition. Azishil 100mg injection shall be given under the skin of your thigh, stomach or upper arm.
Safety Advices for Azishil 100mg Injection
Pregnancy
Consult your doctor
Azishil injection could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.
Breast Feeding
Consult your doctor
Breastfeeding is not intended for patients on Azishil injection therapy. Consult your physician for advice.
Lungs
Consult your doctor
It is not known whether it is safe to administer Azishil injection in lung failure patients. Please consult your doctor.
Liver
Consult your doctor
Inform your physician if you have been told that you have a tumor in the liver cells.
Alcohol
Unsafe
It is not known whether it is safe to consume alcohol with Azishil injection. Please consult your doctor.
Driving
Consult your doctor
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness.
Side Effects of Azishil 100mg Injection
Serious:
- Unexpected bleeding, with blood in stool and urine
- Fever
- Pneumonia, characterized by chest pain or breathlessness.
- Allergic reaction with symptoms of swelling of lips, itching or rashes.
- Seizures, loss of consciousness, severe headache or bleeding in the brain
- Frequent urination with pain or burning sensation
Common:
- Disturbances in the blood count (RBC, WBC, Platelets)
- Nausea, vomiting, diarrhea
- Constipation
- Tiredness
- Skin reaction like redness and pain at the site of injection
- Decreased appetite




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