Anvimo 240mg Tablet

Anvimo 240mg Tablet functions by blocking the CMV DNA terminase complex, a key component required for viral replication. Unlike conventional antiviral drugs that target DNA polymerase, this medication disrupts viral DNA processing and packaging, ultimately preventing the virus from multiplying and spreading in the body.

By stopping CMV replication early in the process, this drug significantly lowers the risk of CMV disease in transplant recipients. The unique mechanism of action makes it highly effective while reducing the likelihood of cross-resistance seen with other CMV treatments. Due to its targeted action, it is well tolerated with a lower risk of severe toxicity compared to older antiviral medications.

Serious drug interactions can alter the effectiveness of Anvimo 240mg Tablet or increase the risk of side effects. Patients should inform their doctor about all medications, including herbal and over-the-counter drugs, before starting this medication.

Notable Drug Interactions:

• Immunosuppressants (e.g., Cyclosporine, Tacrolimus, Sirolimus): Letermovir can increase blood levels of these drugs, requiring dose adjustments.
• Statins (e.g., Simvastatin, Atorvastatin): Increased risk of myopathy or rhabdomyolysis when taken together. Avoid co-administration or monitor closely.
• Anticonvulsants (e.g., Phenytoin, Carbamazepine): May reduce Anvimo 240mg Tablet effectiveness, requiring alternative options.
• Rifampin and St. John’s Wort: These reduce drug efficacy and should be avoided.
• Oral Contraceptives: Letermovir may lower the effectiveness of hormonal birth control, necessitating additional contraceptive methods.

Always consult a doctor before combining this medication with others.

The usual recommended dosage of Anvimo Tablet for CMV prophylaxis is 480 mg once daily. However, if taken in combination with cyclosporine, the dose is reduced to 240 mg daily to prevent excessive drug levels. This medication is available in oral tablets and intravenous (IV) infusion forms. Oral tablets should be swallowed whole with or without food, while the IV infusion must be administered under medical supervision to ensure proper dosing and monitoring.

Common Side Effects:

• Nausea
• Fatigue
• Headache
• Diarrhea
• Abdominal pain

Serious Side Effects:

• Irregular heartbeat
• Swelling in legs or feet
• Unexplained bleeding or bruising
• Severe allergic reactions (rash, breathing difficulty)