Jakavi 15mg Tablet

Introduction to Jakavi 15mg Tablet

Jakavi 15mg tablet contains the active constituent ruxolitinib. It is an anticancer agent that belongs to the class of kinase inhibitors. It is used to treat myelofibrosis ( a rare type of bone marrow cancer that causes decreased blood cell production). It is also used to treat polycythemia vera (a type of blood cancer where the body produces too many red blood cells) in people who are resistant or cannot be treated successfully with other medication hydroxyurea. The medicine is also indicated to treat acute graft versus host disease (a complication of transplant procedure that replaced diseased bone marrow with healthy bone marrow) previously treated unsuccessfully with steroid medications in adults and children 12 years of age. It is also used for treating chronic graft versus host disease in adults and children 12 years of age and older who were treated unsuccessfully with 1 or 2 other systemic treatments.

Jakavi 15mg tablet works by blocking the signals that cause cancer cells to multiply. Do not take this medicine if you are allergic to ruxolitinib or any other ingredients in this medicine. Inform your physician priorly if you have or had tuberculosis, hepatitis B or C, liver disease, and kidney problems. The most common adverse effects are dizziness, reduced blood counts, bruising, bleeding, headache, and facial and body swelling. Notify your physician if you are on dialysis.

Therapeutic Effects of Jakavi 15mg Tablet

Jakavi 15mg tablet, a kinase inhibitor, inhibits dysregulated Janus Associated Kinase (JAK) 1 and JAK2 signaling associated with myelofibrosis and polycythemia vera. By blocking certain enzymes, this medicine can reduce the serious risk of blood or vascular complication in myelofibrosis and polycythemia vera. In GvHD, it reduces the signs and symptoms, improving the disease and survival of transplanted cells.

Interaction of Jakavi 15mg Tablet with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, and supplements and herbal products. Certain medications like fluconazole and other CYP3A4 inhibitors may interact with Jakavi 15mg tablet and reduce its effectiveness by causing undesirable side effects.

More Information about Jakavi 15mg Tablet

Do not store this medicine above 30°C
Keep the medicine out of reach from children and pets
If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

How to consume Jakavi 15mg Tablet

Your doctor will decide the dose and duration of Jakavi 15mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Safety Advices for Jakavi 15mg Tablet

Pregnancy

Do not take Jakavi 15mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment.

Breast Feeding

Breastfeeding is not recommended in patients taking Jakavi 15mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment and for 2 weeks after the last dose.

Lungs

It is unknown whether Jakavi 15mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

Jakavi 15mg tablet should be administered cautiously in patients with liver problems. Dose adjustments are necessary for patients with liver diseases. Inform your physician if you have any liver disorder before the treatment.

Alcohol

It is unknown whether consuming alcohol is safe when taking Jakavi 15mg tablet. Inform your physician if you are an alcoholic before starting the treatment.

Driving

Do not drive or operate heavy machinery if you feel dizzy after taking Jakavi 15mg tablet. Consult your doctor for more advice.

Side Effects of Jakavi 15mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

Low red and white blood cell counts
Low platelet counts
Dizziness, headache
Bruising
Diarrhea
Infections including viral infection
Swelling in the face and body
Fatigue or tiredness

Serious

Severe infections like hepatitis B
Anemia
Bleeding

Brand

Novartis

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