PEG Frastim 6mg Injection

Introduction to Peg Frastim 6mg Injection

Peg Frastim 6mg Injection contains the active ingredient Pegfilgrastim. It belongs to the class granulocyte colony stimulated factor approved by FDA to decrease the risk of developing febrile neutropenia ( occurrence of fever or infection with low WBC count) and the duration of neutropenia (Low white blood cell count) when receiving bonemarrow suppressive chemotherapy drugs. It is also indicated to increase survival rate in patients exposed to radiation therapy which can cause severe and life-threatening damage to bone marrow. It acts on blood-forming cells, thereby stimulating cell multiplication and cell function activation.

Pegfilgrastim is a protein synthesized through biotechnology in E. coli bacteria. It belongs to the cytokine family of proteins and is very similar to a natural protein (granulocyte-colony stimulating factor) produced by your body. White blood cells (WBC) are important because they help your body fight infection. These cells are highly sensitive to the effects of chemotherapy, which might cause a decrease in the number. If your WBC decreases, your body may not have enough cells to combat bacteria, putting you at risk of infection.

Inform your physician if you have or ever had liver disease, fever or infection, kidney problems, heart problems, or a family history of kidney diseases before starting the treatment with this Injection. Do not take this Injection if you are allergic to pegfilgrastim. Filgrastim or any of the other ingredients in this Injection. Report any symptoms of left upper abdominal pain, shoulder pain, and respiratory problems immediately to your doctor. The most common side effects of Peg Frastim 6mg injection are pain in the bones, arms, and legs.

Therapeutic Effects of Peg Frastim 6mg Injection

Peg Frastim 6mg Injection is a colony-stimulating factor that exerts its action by acting on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation.

Interaction of Peg Frastim 6mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Peg Frastim 6mg Injection and reduce effectiveness by causing undesirable side effects.

More Information about Peg Frastim 6mg Injection

Store Peg Frastim 6mg Injection in a refrigerator (2°C – 8°C). Do not freeze.
Do not shake this Injection
Discard the Injection if it has been stored at room temperature for more than 48 hours.
Keep it out of reach from children and pets.
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor immediately for advice.

How to consume Peg Frastim 6mg Injection

The Injection will be administered in the fatty tissues just under your skin (subcutaneously) by a qualified healthcare professional in a hospital setting. The dose and frequency of administration will be decided by your doctor based on your disease condition and other factors.

If your physician decides that Peg Frastim 6mg Injection can be administered at home by you or your caregiver, then read the “Instructions for use” carefully from the package insert that comes with the Injection. Your doctor or other healthcare professionals will train you on self-administration. Do not administer the Injection if you have not been trained and not sure about the administration procedure.

Safety Advices for Peg Frastim 6mg Injection

Pregnancy

Peg Frastim 6mg Injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Breast Feeding

It is unsafe to breastfeed during the treatment with this Peg Frastim 6mg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.

Lungs

It is unknown whether Peg Frastim 6mg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

It is unknown whether Peg Frastim 6mg Injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.

Alcohol

It is unsafe to consume alcohol with Peg Frastim 6mg Injection. Please consult your doctor for more advice.

Driving

It is unsafe to travel, drive vehicles or operate heavy machinery after taking (1 hour) Peg Frastim 6mg Injection. Please consult your doctor.

Side Effects of Peg Frastim 6mg Injection

Side effects are unwanted symptoms caused by Injections. Even though all drugs cause side effects, not everyone gets them.

Common

Pain in the bones, joints and muscles
Pain at the site of Injection
Itchiness and skin rash
Nausea
Headaches
Dizziness and tiredness

Serious

Inflammation of Aorta
Capillary leak syndrome (plasma leaks out of tiny blood vessels)
Hypersensitivity reactions
Changes in urine color
Swelling in hands, feet, face, and abdomen
Difficulty in breathing
Sickle cell anemia

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