Introduction to Votrient 400mg Tablet
Votrient 400mg tablet contains the active substance pazopanib. It is an antineoplastic drug in the tyrosine kinase inhibitor class. It is used in adults to treat advanced kidney cancer that has spread to other organs.
Do not take Votrient 400mg tablet if you are allergic to Pazopanib or any other ingredients of this medicine. Before initiating the treatment, inform your physician if you have kidney, heart, lung, or liver problems, bleeding disorders, stomach or bowel problems, and thyroid problems. This tablet can raise your blood pressure, so you should check it regularly during treatment. No dose adjustments are required for patients with kidney diseases.
Your doctor will advise you to stop Votrient 400mg tablet at least 7 days before any surgeries or dental operations that you are undergoing, as it may affect wound healing. This medicine is not recommended for people aged under 18. This medicine can cause infertility; consult your doctor before taking this medicine. The most common side effects are diarrhea, hypertension, hair color changes, nausea, and vomiting.
Therapeutic Effects of Votrient 400mg Tablet
Votrient 400mg tablet is a biological agent that acts as targeted drug therapy in cancer treatment. It interferes with the growth of blood vessels inside the cancer cells by acting against a protein called Vascular Endothelial Growth Factors (VEGF) to shrink cancer cells, ultimately stopping their growth and multiplication.
Interaction of Votrient 400mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Votrient 400mg tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Votrient 400mg Tablet
- Store Votrient 400mg tablet in room temperature (25°C)
- Keep the injection away from the reach of children and pets.
- If you forgot to take a dose, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose.
- Take only a partial dose to make up for a forgotten dose.
How to consume Votrient 400mg Tablet
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Do not take this medicine with food, as it affects the absorption of this medicine. Take Votrient 400mg tablet at least two hours after a meal or one hour before a meal.
Safety Advices for Votrient 400mg Tablet
Pregnancy
Votrient 400mg tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 2 weeks after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Votrient 400mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Votrient 400mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Votrient 400mg tablet is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary for moderate liver failure. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unknown whether it is safe to consume alcohol when taking Votrient 400mg tablet. Consult your doctor for more advice.
Driving
Driving or operating heavy machinery is unsafe after taking Votrient 400mg tablet because you may feel dizzy, drowsy, or have blurred vision.
Side Effects of Votrient 400mg Tablet
It is crucial to monitor any adverse effects and report them to your healthcare provider for appropriate management.
Common
- Hypertension
- Hair color change
- Increased glucose levels
- Decreased weight, decrease in appetite
- Diarrhea
- Nausea, vomiting
- Muscle and joint pain
- Headache
- Shortness of breath
- Tiredness
Serious
- Heart problems
- Bleeding from the anus, mouth
- Hypothyroidism
- Interstitial lung disease
- Infections
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