zevtaxel 60mg injection

Introduction to Zevtaxel 60mg Injection

Zevtaxel 60mg Injection contains the active constituent cabazitaxel. It is an anticancer medicine used with steroid medicine prednisone or prednisolone to treat people with hormone-refractory metastatic prostate cancer that has progressed after treatment with other anticancer medications, including docetaxel. Cancer is an abnormal and uncontrolled multiplication of cells. Many early-stage prostate cancers need normal testosterone (male hormone) levels to grow. In hormone-refractory metastatic prostate cancer, cancer keeps growing even when the amount of testosterone in the body is reduced to low levels. This medicine should not be used if you have a severe abnormal liver function or have recently been vaccinated against yellow fever.

Its major toxicities include myelosuppression, neurotoxicity, and allergic reactions. Neutropenia is the most common adverse reaction to this drug. Monitoring of complete blood counts is essential on a weekly basis during cycle 1 and before each treatment cycle thereafter so that the dose can be adjusted, if needed. Vaccination with a live attenuated vaccine should be avoided in patients receiving the medicine, instead killed or inactivated vaccines can be administered.

Consult your doctor before using this medication if you are pregnant or plan to have a baby. This drug is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with this drug. Discuss with your doctor effective birth control methods and utilize them for at least two weeks following the last dose. Avoid breastfeeding your baby while on the treatment as it is unknown if this drug passes into the breast milk.

Therapeutic Effects of Zevtaxel 60mg Injection

It is a mitotic inhibitor that works by disrupting the normal process of cell division. This interferes with the microtubules that help to form the cell’s cytoskeleton. Microtubules are essential for the normal process of cell division, as they help to pull apart the chromosomes during mitosis. By inhibiting microtubules, this drug prevents the cancer cells from dividing properly and ultimately leads to their death.

Interaction of Zevtaxel 60mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Zevtaxel 60mg Injection and reduce effectiveness by causing undesirable side effects.

More Information about Zevtaxel 60mg Injection

Store Zevtaxel 60mg injection in the original package at room temperature (30°C).
Do not refrigerate.

How to consume Zevtaxel 60mg Injection

The medicine will be administered to you by a healthcare professional in a hospital setting. The recommended dose for this drug is 25mg, administered as an intravenous infusion over one hour every three weeks, in combination with oral prednisone (10 mg daily). The dose can be adjusted based on individual patient factors, such as age, body weight, and other medical conditions.

Safety Advices for Zevtaxel 60mg Injection

Pregnancy

It is unsafe to use during pregnancy whether Zevtaxel 60mg injection can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Breast Feeding

It is unsafe to breastfeed during the treatment with this Zevtaxel 60mg injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.

Lungs

It is unknown whether Zevtaxel 60mg injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

It is unknown whether Zevtaxel 60mg injection can be used for patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this drug.

Alcohol

It is unknown whether consuming alcohol interacts with the Zevtaxel 60mg injection. Please consult your doctor for more advice.

Driving

It is unsafe to drive vehicles or operate heavy machinery after taking the Zevtaxel 60mg injection because it contains a small amount of alcohol which may cause dizziness and impair your concentration.

Side Effects of Zevtaxel 60mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

Low white blood cells
Infection (fever, cough, muscle aches, burning on urination)
Severe allergic reactions (rash, itching, breathing problems, swelling of face, chest, or throat tightness)
Kidney damage
Severe stomach pain

Common

Low red blood cell count
Low blood platelet count
Constipation
Back pain, joint pain
Decreased appetite
Hair loss
Numbness, burning, tingling, or decreased sensation in your feet or hands
Taste change
Headache, dizziness
Inflammation of the mouth
Blood in urine

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