Natdecita 50mg Injection

Introduction to Natdecita 50mg Injection

Natdecita 50mg injection contains the active substance decitabine. It is an antineoplastic drug that belongs to the class of medications called DNA methylation inhibitors. It is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and do not produce enough healthy blood cells). It is also used to treat a type of cancer called acute myeloid leukemia (AML). It works by stopping the cancer cells from growing.

Do not take this injection if you are allergic to Natdecita 50mg injection or any other ingredients of this medicine. Inform your physician if you have an infection, decreased blood cell count, liver disease, kidney disorder, and a heart disorder. This medicine is not recommended for children or young people below 18 years of age. This medicine can cause a serious immune reaction called differentiation syndrome. Report to your physician if you face any symptoms of sudden difficulty in breathing, cough, fever, or swelling in the body.

Natdecita 50mg injection should not be used in pregnant and breastfeeding women. Inform your physician if you are pregnant or breastfeeding. Use effective contraception throughout the therapy to avoid pregnancy. The common adverse reactions are decreased white blood cells, red blood cells, platelet counts, and increased body temperature.

Therapeutic Effects of Natdecita 50mg Injection

Natdecita 50mg injection promotes hypomethylation of DNA and cellular differentiation or cell death after phosphorylation, direct incorporation into DNA, and inhibition of DNA methyltransferase. It works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.

Interaction of Natdecita 50mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Natdecita 50mg injection and reduce its effectiveness by causing undesirable side effects.

More Information about Natdecita 50mg Injection

Do not store it above 25°C
keep the injection away from the reach of children and pets.
If you have missed any dosing appointments, inform your doctor and schedule immediately.

How to consume Natdecita 50mg Injection

It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). This will take one hour. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

Safety Advices for Natdecita 50mg Injection

Pregnancy

Natdecita 50mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6 months after your last dose is necessary.

Breast Feeding

Breastfeeding is not recommended in patients taking Natdecita 50mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Lungs

It is unknown whether Natdecita 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

It is unknown whether Natdecita 50mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.

Alcohol

It is unknown whether consuming alcohol is safe during the treatment with Natdecita 50mg injection. Inform your doctor if you are a chronic drinker.

Driving

Natdecita 50mg injection may make you feel tired, dizzy, or sleepy. It is unsafe to drive or operate heavy machinery after taking this medicine.

Side Effects of Natdecita 50mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

Swelling in the face, hands, and feet
Swelling and pain in the skin
Discoloration of the skin
Increased blood sugar levels
Decreased albumin levels
Abdominal pain, constipation
Decrease in appetite
Diarrhea, indigestion
Nausea, vomiting
Insomina, dizziness
Pain in limbs

Serious

Heart problems
Anemia
Infection
Bleeding
Fluid in the lungs
Pneumonia

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